Alternative splicing; Blinatumomab; CD19; Exitrons; Immunotherapy; Long-read sequencing; Oxford Nanopore Technologies; Reverse transcription; mRNA isoforms

Direct long-read RNA sequencing identifies a subset of questionable exitrons likely arising from reverse transcription artifacts
Resistance to CD19-directed immunotherapies in lymphoblastic leukemia has been attributed, among other factors, to several aberrant …
Laura Schulz, Manuel Torres-Diz, Mariela Cortés-López, Katharina E Hayer, Mukta Asnani, Sarah K Tasian, Yoseph Barash, Elena Sotillo, Kathi Zarnack, Julian König, Andrei Thomas-Tikhonenko
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